Experimental Biophotonics 

Advanced light microscopy R&D areas:

  • Research on novel approaches in advanced light microscopy, especially holographic and two‑photon microscopy.
  • Theoretical study and numerical simulation of coherence effects in holographic microscopy, imaging in turbid media and axial localization based on coherence gating.
  • Development of advanced image-processing methods for holographic reconstruction, quantitative phase imaging (QPI), as well as pattern and process recognition and/or classification.

Applications in cell biology, cancer and neuroscience research:

  • Identification and classification of behavioural patterns in live cancer cells including biopsy-derived carcinoma cells using coherence-controlled holographic microscopy (CCHM).
  • Development of a strategy for personalized cancer treatment based on live-cell dry-mass profiling.
  • Investigation of cellular and molecular aspects of the hemodynamic response of the brain.

Applications in nanotechnology:

  • Novel methods of plasmonic phenomena observation in nanostructures with CCHM.



Published paper "Automated interpretation of time-lapse…

​New paper by Dr. Lenka Štrbková "Automated interpretation of time-lapse quantitative phase image… Read more »


Published paper "Optical topography of rough surfaces using…

New paper by Dr. Petr Schovánek, in collaboration with Dr. Petr Bouchal and prof. Zdeněk Bouchal "Optical topography of… Read more »


Published paper "Dual Targeting of BRAF and mTOR Signaling in…

New paper by Veronika Palušová, in collaboration with Dr. H. Uhlířová, Dr. A. Křížová, MUDr. P. Veselý… Read more »