​​Advanced light microscopy R&D areas:

  • Research on novel approaches in advanced light microscopy, especially holographic and two‑photon microscopy.
  • Theoretical study and numerical simulation of coherence effects in holographic microscopy, imaging in turbid media and axial localization based on coherence gating.
  • Development of advanced image-processing methods for holographic reconstruction, quantitative phase imaging (QPI), as well as pattern and process recognition and/or classification.

Applications in cell biology, cancer and neuroscience research:

  • Identification and classification of behavioural patterns in live cancer cells including biopsy-derived carcinoma cells using coherence-controlled holographic microscopy (CCHM).
  • Development of a strategy for personalized cancer treatment based on live-cell dry-mass profiling.
  • Investigation of cellular and molecular aspects of the hemodynamic response of the brain.

Applications in nanotechnology:

  • Novel methods of plasmonic phenomena observation in nanostructures with CCHM.



CEITEC reports about our research achievements

CEITEC reports about our research in the post "New method for imaging live tumor cells allows analysis of… Read more »


Published paper "Geometric-phase microscopy for quantitative…

New paper by Dr. Petr Bouchal "Geometric-phase microscopy for quantitative phase imaging of isotropic,… Read more »


Published paper "High-Resolution Quantitative Phase Imaging of…

New paper by Dr. Petr Bouchal "High-Resolution Quantitative Phase Imaging of Plasmonic Metasurfaces with Sensitivity… Read more »